Lactobacillus acidophilus D2/CSL (CECT 4529) in authorized as gut flora stabiliser for dogs and cats by Regulation (EU) 2018/1558 of 17 October 2018. 


Gut flora and gastrointestinal dysbiosis

One of the major functions of the gastrointestinal microbiota (or “gut flora”) is the ability to resist invasion by exogenous organisms, working together with the other host’s non-specific defences and the gut-associated immune system.However, the balance among GI microbial communities change over time, due to physiological and/or environmental causes, including ageing, dietary change, dietary restriction, stress, challenge of pathogens, and antimicrobial treatment.

Some alterations in the GI microbiota, or dysbiosis, can affect animal health, e.g. by lowering the body condition, or increasing fecal humidity and fecal score.More severe GI dysbiosis can produce profound negative effects on gut physiology and health, including acute and chronic GI inflammation.

In human medicine, probiotic lactobacilli have been used to manage a number of disorders related to GI dysbiosis, such as antibiotic-associated diarrhea, intestinal infection, and mucosal inflammation.

Lactobacillus acidophilus D2/CSL (CECT 4529) improves gut health and the well-being of your animal friends!

Lactobacillus acidophilus is a natural inhabitant of the gastrointestinal tract of dogs and cats.

Lactobacilli become established in the GI tract of dogs and cats soon after birth, inhibiting the proliferation of enterobacteria and other unwanted bacteria (e.g. Clostridium perfringens and Escherichia coli).

Unfortunately, the relative abundance of intestinal lactobacilli vary over time, so dysbiosis due to an imbalance between lactobacilli and unwanted bacteria are commonly observed in dogs and cats.

A series of studies provide a clear evidence of Lactobacillus acidophilus D2/CSL (CECT 4529) as “gut flora stabiliser” for dogs and cats.

The probiotic positively influences the welfare of the animals by increasing their gut health and in turn the quality of their stools, restoring the nutritional functions to physiological levels.

In consequence of the improved digestive functions, dogs receiving Lactobacillus acidophilus D2/CSL (CECT 4529) improve their body condition score.

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